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I've posted more details here: http://fpv-community.de/showthread.php?67660-Baubericht-Umbau-Prusa-i3-zu-Laser-Gravierer-(inkl-Firmware-f%FCr-samelladrucker)

You may want to use google translator or just visit http://jtechphotonics.com/?page_id=1503 for more.

Focusing is done by adjusting the lasers' lens or the Z height via gcode or display if you have that connected... Or just turn the two Z couplings manually. After all this is not much of a problem.