MakerBot Print is our newest print-prepration software, which supports native CAD files and STL assemblies,
allows you to interact with all your printers via the Cloud, and many other exciting new features.

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Yes and depends. Depends upon what firmware you choose to use. Jetguy has his 4foot by 4foot by 1meter corexy bot using Sailfish and it works fine. Even then incredibly large numbers of steps can be broken into two (or more) moves but we're talking, IIRC, things exceeding 524287 steps in a single move along any one axis.