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MakerBot Print is our newest print-prepration software, which supports native CAD files and STL assemblies,
allows you to interact with all your printers via the Cloud, and many other exciting new features.

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Thanks! The Up/Afinia has a "Pause Print" feature for filament changes. It lowers the bed a couple of inches and keeps the extruder hot while you change. You can set automatic pause points prior to slicing if you want to, but in this case I just watched the print and did it manually.