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MakerBot Print is our newest print-prepration software, which supports native CAD files and STL assemblies,
allows you to interact with all your printers via the Cloud, and many other exciting new features.

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I personally really like Cura, haven't used prusaslicer. I keep flow rate at 100%, maybe 99 if im printing certain PETG filaments. I use Klipper so I disable acceleration and jerk control in the slicer. The acceleration that I use for all my prints is 2500 which I set in the klipper config file