MakerBot Print is our newest print-prepration software, which supports native CAD files and STL assemblies,
allows you to interact with all your printers via the Cloud, and many other exciting new features.
Since this also adds a custom machine profile to prevent Cura screwing with the jerk and acceleration settings, this can cause conflicts. Try renaming your existing profile.
Also, I'm currently using Cura 4.1. I will upgrade to 4.2.1 and see if it has trouble importing the profile; if so, I'll try to fix the problems.