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Using different slicer can be reason for different experience with fit of the parts. For me none of the connection is really tight but the small gear is critical because it can fall off and the spool stops rewinding at all. I helped myself with some small pieces of filament making all connection tight.
I have read in some discussion that regardless the Extrussion multiplier seting in Slic3r PE or Prusaslicer there is "M221 S95" command in every gcode file from these slicers as some compensation. This can explain different results of prints from Simplify3D and Prusaslicer.