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MakerBot Print is our newest print-prepration software, which supports native CAD files and STL assemblies,
allows you to interact with all your printers via the Cloud, and many other exciting new features.

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It depends on what software you are using to slice the model for printing. I use Cura to slice and to reduce the amount of spool used I print with less infill(10-18%), only 2 lines of wall thickness. Try printing the large base upside down to reduce supports