MakerBot Print is our newest print-prepration software, which supports native CAD files and STL assemblies,
allows you to interact with all your printers via the Cloud, and many other exciting new features.
For best results, I would keep it in this exact orientation. The best way to build supports for this is to use meshmixer (don't worry, its free!) and then slice it in Cura. If you click the following link, you can look at one of the models i uploaded with an example of what the supports should look like in meshmixer (it is the 7th picture from the start). The nice part about meshmixer is you can click and choose which supports you do and don't want. If you think something needs more support, just click and drag from the two points you'd want the support to hold. Let me know if you have any other questions: